Oslo, February 7, 2019 The recent Proof of Mechanism shown for CRX demonstrates the dynamic properties of this product obstructing both of the well-known virus entry mechanisms CCR5 and CXCR4 in a way that prevents the virus from evading the blockage through escape mutations. The product CRX constitutes the 3rd of the three cornerstones of …
Oslo, January 23, 2019. Bionor is pleased to announce that Proof of Mechanism is established for our 3rd vaccine candidate, CRX. This product aims to prevent binding between gp120 V3 loop and CCR5/CXCR4 coreceptors and facilitate virus neutralization. Lead optimization and drug characterization with Proof of Principle will be established within the next 6 – …
Bionor’s strategy is to develop the combination of its two proprietary therapeutic HIV vaccines Vacc-4x and Vacc-C5 and seek advice on and adapt its regulatory path so that a marketing approval for a functional cure for HIV can be achieved. As part of this strategy, Bionor will extend and complete the Vacc-C5 dose escalation studies …
